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Assessment of Airways Mechanical Properties by FOT and LIR During Anesthesia

NCT01506284 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14

Last updated 2014-12-09

No results posted yet for this study

Summary

The aims of the present study are:

1. To evaluate the effect of the induction of anaesthesia and paralysis in terms of changes in oscillatory mechanics parameters
2. To evaluate the mechanical properties of the respiratory system in terms of input and transfer oscillatory impedance in response to PEEP changes

Conditions

  • Anesthesia

Interventions

PROCEDURE

Forced oscillatory technique (FOT) and laser interferometry (LIR).

FOT: The stimulating signal is generated by an A/D-D/A board and amplified by a power amplifier that drives a loudspeaker the output of which is connected to inspiratory line of the ventilator. Pressure and flow are measured at the inlet of the endotracheal tube by a piezoresistive pressure transducer and a mesh-type heated pneumotachograph coupled with a differential pressure transducer. LIR: The scanner unit is made by three laser interferometers, the beams of which are deflected on the chest wall surface by a mirror moved by a stepper motor triggered on the respiratory pattern of patient.

Sponsors & Collaborators

  • Politecnico di Milano

    collaborator OTHER

  • Uppsala University Hospital

    lead OTHER

Principal Investigators

  • Peter Frykholm, MD, PhD · Uppsala University Hospital

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2012-03-31
Completion
2012-11-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01506284 on ClinicalTrials.gov