Integrated Molecular Profiling in Advanced Cancers Trial
NCT01505400 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 3026
Last updated 2026-01-08
Summary
Substantial progress has been made in the treatment of cancer through the use of targeted therapies, but what works for one patient might not work for another patient. Certain drugs are now being developed that target specific molecules in the body that are believed to be part of the disease.
Biomarkers are specific characteristics of the cancer that may help provide prognostic information (i.e. how well patients will be regardless of the treatments given) or help predict sensitivity or resistance to a specific treatment.
The study will collect archival tumor samples (previously collected biopsy or surgical tumor samples) to provide biomarker data about a patient's cancer, in order to help their physicians to identify which clinical trials of molecularly targeted therapies may be most appropriate for the patient in the future.
Conditions
- Breast Cancer
- Non-small Cell Lung Cancer
- Colorectal Cancer
- Genitourinary Cancer
- Pancreatobiliary Gastrointestinal Cancer
- Upper Aerodigestive Tract Cancer
- Gynecological Cancers
- Melanoma Cancers
- Rare Cancers
- Unknown Primary Cancers
Sponsors & Collaborators
-
Princess Margaret Hospital, Canada
collaborator OTHER -
University Health Network, Toronto
lead OTHER
Principal Investigators
-
Philippe Bedard, MD · Princess Margaret Hospital, Canada
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-02-29
- Primary Completion
- 2027-01-31
- Completion
- 2027-01-31
Countries
- Canada
Study Locations
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