Effect of Transmagnetic Stimulation on Conditioned Pain Modulation (CPM)
NCT01501045 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 94
Last updated 2019-03-27
Summary
While some indications of the neural circuits involved in the Conditioned Pain Modulation (CPM) process are now available, there is still need to clarify what parts of the brain are essential for this process, whether the spino-brainstem loop is largely sufficient to explain CPM or whether other cerebral and spinal regions such as frontal, somatosensory and other cortical regions contribute substantially. Whereas mere observation of correlation between these circuits while activated by brain imaging is still of considerable interest, direct experimental manipulations by repetitive transcranial magnetic stimulation (rTMS) could even establish insights into causal relationships.
Conditions
Interventions
- DEVICE
-
TMS system MagPro x100, Tonica Elektronik A/S, Denmark
repeated TMS (rTMS)
- DEVICE
-
TMS system MagPro x100, Tonica Elektronik A/S, Denmark
repeated TMS
Sponsors & Collaborators
-
German Research Foundation
collaborator OTHER -
Rambam Health Care Campus
lead OTHER
Principal Investigators
-
David Yarnitsky, professor · Rambam Health Care Campus
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-01-31
- Primary Completion
- 2017-11-06
- Completion
- 2017-11-06
Countries
- Israel
Study Locations
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