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Single Human Embryo Transfer in Assisted Reproduction Programs

NCT01471951 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 154

Last updated 2011-11-16

No results posted yet for this study

Summary

Embryo selection based on the use of morphometric parameters should increase the implantation success rate.

One of the most important issues of "Assisted Reproduction Technologies (ART)" is the possibility of multiple pregnancies which carries a significant risk for maternal-fetal health. These risks can be reduced by restricting the number of embryos transferred.

To do this, it is essential to improve current techniques of embryo selection by developing new tools that would allow the selection of the embryos with higher implantation potential. In previous works (Molina et al 2011) the investigators have demonstrated greater efficacy for the embryo classification systems based on the use of the morphometric variables. The investigators have also developed a profile of embryo implantation using these morphometric variables. In this project the investigators intend to validate the clinical validity of this new embryo classification system by conducting a prospective study of single embryo transfer (SET) in young women at risk of multiple pregnancies.

Conditions

  • Multiple Pregnancies

Interventions

OTHER

Single embryo transfer in women at risk of multiple pregnancies

Prospective study of single embryo transfers in selected women with good reproductive prognosis and high risk of multiple pregnancies in an IVF-ICSI program.. The day of the embryo transfer, the patients will be randomized by a computer application for morphological and morphometric embryo selection.

Sponsors & Collaborators

  • Fundacion Para La Investigacion Hospital La Fe

    lead OTHER

Principal Investigators

  • Jose J Pertusa, Ph.D. · Director of the deparment of Biología Funcional y Análisis de Imagen

  • Antonio A Pellicer, Ph.D. · Head of Gynecology and Obstetrics

  • Inmaculada I Molina, Ph.D. · Embryologist of the Human Reproduction Unit

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2013-12-31
Completion
2014-06-30

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01471951 on ClinicalTrials.gov