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Oral Contraceptives and Subantimicrobial Doxycycline: Effect on Endometrial Matrix Metalloproteinases

NCT01469585 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-12-17

Study results available
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Summary

The purpose of this study is to compare the effects (good and bad) of subantimicrobial dose doxycycline on the irregular bleeding women experience when taking continuous oral contraceptive pills. This research is being done because currently, there is no effective treatment for this condition. Findings from this study could help to decrease the side effects of birth control pills and decrease unplanned pregnancies.

Conditions

  • Breakthrough Bleeding

Interventions

DRUG

Doxycycline

40 mg orally at the start of cycle 3 (study day 57) for 28 days.

Sponsors & Collaborators

  • Charles Drew University of Medicine and Science

    collaborator OTHER

  • Meharry Medical College

    collaborator OTHER

  • University of Hawaii

    lead OTHER

Principal Investigators

  • Bliss Kaneshiro, MD, MPH · University of Hawaii John A. Burns School of Medicine Department of Obstetrics and Gynecology

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2012-05-31
Completion
2012-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01469585 on ClinicalTrials.gov