Reversing Hormone Resistance in Advanced Breast Cancer With Pazopanib
NCT01466972 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2020-07-08
Summary
The purpose of this study is to evaluate the clinical benefit rate at 12 weeks from the addition of pazopanib to a non-steroidal aromatase inhibitor (NSAI) (letrozole or anastrozole) in patients with hormone receptor positive advanced breast cancer progressing on the same NSAI hormone therapy.
Conditions
- Breast Cancer
- Breast Neoplasm
Interventions
- DRUG
-
Pazopanib
Oral, 800mg tablet daily per cycle
Sponsors & Collaborators
- collaborator INDUSTRY
-
Hope Rugo, MD
lead OTHER
Principal Investigators
-
Hope Rugo, M.D. · University of California, San Francisco
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-04-27
- Primary Completion
- 2015-12-07
- Completion
- 2019-10-02
- FDA Drug
- Yes
Countries
- United States
Study Locations
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