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Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness

NCT01462279 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2018-01-16

Study results available
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Summary

The objective of this study is to determine the effect of thiamine therapy on oxygen consumption in critically-ill patients. The investigators will evaluate this by measuring VO2 before and after thiamine administration in patients admitted to the ICU and requiring mechanical ventilation.

Conditions

  • Acute Respiratory Failure

Interventions

DRUG

Thiamine

200mg of intravenous thiamine in 50ml of D5W will be infused over 30 minutes once

Sponsors & Collaborators

Principal Investigators

  • Katherine M Berg, MD · Beth Israel Deaconess Medical Center

  • Michael W Donnino, MD · Beth Israel Deaconess Medical Center

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2012-10-31
Completion
2012-10-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01462279 on ClinicalTrials.gov