Indirect Comparison of Tobramycin Solution for Inhalation Versus Aztreonam Lysine for Inhalation in the Treatment of Cystic Fibrosis
NCT01460836 · Status: COMPLETED · Type: OBSERVATIONAL
Last updated 2011-10-27
Summary
Matching-adjusted indirect comparison of tobramycin solution (TIS) versus aztreonam lysine (AZLI) using TIS patient level clinical trial data and AZLI aggregated clinical trial data from published literature.
Conditions
Interventions
- DRUG
-
Tobramycin solution for inhalation
- DRUG
-
Aztreonam lysine for inhalation
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmaceuticals
Eligibility
- Min Age
- 6 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-04-30
- Primary Completion
- 2010-10-31
More Related Trials
-
A Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI®
NCT00885365 ·Status: COMPLETED ·Phase: PHASE3
-
Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis
NCT00388505 ·Status: COMPLETED ·Phase: PHASE3
-
Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Subjects
NCT00125346 ·Status: TERMINATED ·Phase: PHASE3
-
Tobramycin 300 mg Once-a-day (o.d.) Aerosol in Adults With Cystic Fibrosis
NCT01608555 ·Status: COMPLETED ·Phase: PHASE4
-
Tobramycin Inhalation Solution Administered by eFlow Rapid Nebulizer: Scintigraphy Study
NCT00399945 ·Status: COMPLETED ·Phase: PHASE1
-
Randomized, Controlled Study of CF Patients Between 3 Months and Less Than 7 Years
NCT01082367 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis
NCT03066453 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy of TOBI Podhaler vs. Tobramycin Inhalation Solution
NCT02038803 ·Status: TERMINATED
-
Long Term Safety of Tobramycin Inhalation Powder in Patients With Cystic Fibrosis
NCT01519661 ·Status: COMPLETED ·Phase: PHASE4
-
Tobramycin Inhalation Powder (TIP) Administered Once Daily Continuously Versus TIP Administered BID in 28 Day on / 28 Day Off Cycles
NCT02015663 ·Status: TERMINATED ·Phase: PHASE4
-
A Single Arm 48-Week Follow-on Safety Study to a Core Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI®
NCT01111383 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis
NCT00006280 ·Status: COMPLETED ·Phase: PHASE2
-
Pharmacokinetic Evaluation of an 8 -Week Treatment With Inhaled Tobramycin
NCT00634192 ·Status: COMPLETED ·Phase: PHASE3
-
Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis
NCT02657473 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection
NCT00794586 ·Status: COMPLETED ·Phase: PHASE2
-
Pharmacokinetic Evaluation and Tolerability of Dry Powder Tobramycin by a Novel Device in Patients With Non Cystic Fibrosis Bronchiectasis
NCT02035488 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Dose-finding Study to Assess the Efficacy, Safety and Tolerability of Tobramycin Inhalation Powder in Patients With Non-Cystic Fibrosis Bronchiectasis and Pulmonary P. Aeruginosa Infection
NCT02712983 ·Status: COMPLETED ·Phase: PHASE2
-
Second Open Label Extension to Bridging Study CTBM100C2303
NCT01069705 ·Status: COMPLETED ·Phase: PHASE3
-
OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis
NCT02054156 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of the Clinical Benefit of Tobramycin Inhalation Solution
NCT06106789 ·Status: ACTIVE_NOT_RECRUITING
-
Evaluation of Inhaled Antibiotics on Bacterial Diversity and Richness in the Cystic Fibrosis Lung
NCT02113397 ·Status: TERMINATED
-
Phase 3 Study of Aztreonam for Inhalation Solution (AZLI) in a Continuous Alternating Therapy Regimen for the Treatment of Chronic Pseudomonas Aeruginosa Infection in Patients With CF
NCT01641822 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Tobramycin Inhalation Powder From a Modified Manufacturing Process Versus Placebo
NCT00918957 ·Status: COMPLETED ·Phase: PHASE3
-
Nasal Inhalation of Tobramycin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization
NCT00774072 ·Status: COMPLETED ·Phase: PHASE2
-
Combined Dry Powder Tobramycin and Nebulized Colistin Inhalation in CF Patients
NCT03341741 ·Status: COMPLETED ·Phase: PHASE3