Syndecan-1 a Surrogate Marker for IBD
NCT01430039 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 42
Last updated 2015-04-08
Summary
Syndecan-1 is a protein on the surface intestinal cells. previous studies proved low levels of mucosal syndecan-1 levels on the surface of intestinal cells is patients with acute and chronic inflammation due to inflammatory bowel disease.
this protein might shed from cell surface to the serum. The investigators wish to prove that elevated serum levels of syndecan-1 may be predictive of disease presence, extent and severity, that buy taking a simple blood sample from patients diagnosed with inflammatory bowel disease and comparing to normal subjects and to other markers.
Conditions
- Inflammatory Bowel Diseases
Interventions
- PROCEDURE
-
blood sample
Blood sample from a peripheral vein, 10ml total for blood count, total serum : protein, albumin, LDH, C-reactive protein,syndecan-1
- PROCEDURE
-
Blood sample - venous blood 10 ml.
venous blood sample from a peripheral vein, 10ml total for blood count, total serum : protein, albumin, LDH, C-reactive protein,syndecan-1
Sponsors & Collaborators
-
Meir Medical Center
lead OTHER
Principal Investigators
-
Assaf Stein, Md · resident
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-10-31
- Primary Completion
- 2015-04-30
- Completion
- 2015-04-30
Countries
- Israel
Study Locations
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