Biomarkers in Samples From Adult Patients With Acute Myeloid Leukemia Who Failed Existing Standard-of-Care Treatment
NCT01421862 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 400
Last updated 2013-07-10
Summary
RATIONALE: Studying samples of bone marrow and blood from patients with cancer who failed treatment may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer resistance. It may also help doctors find better ways to treat cancer.
PURPOSE: This research trial studies biomarkers in samples from adult patients with acute myeloid leukemia who failed standard-of-care treatment.
Conditions
Interventions
- GENETIC
-
DNA methylation analysis
- GENETIC
-
RNA analysis
- GENETIC
-
gene expression analysis
- GENETIC
-
microarray analysis
- GENETIC
-
mutation analysis
- GENETIC
-
nucleic acid sequencing
- OTHER
-
laboratory biomarker analysis
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Jerry Radich, MD · Fred Hutchinson Cancer Center
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-09-30
- Primary Completion
- 2011-10-31
More Related Trials
-
Biomarkers in Predicting Response to Treatment in Bone Marrow Samples From Young Patients With Acute Myeloid Leukemia
NCT01321385 ·Status: COMPLETED
-
S0106B Studying Bone Marrow Samples From Women With Acute Myeloid Leukemia
NCT01575535 ·Status: COMPLETED
-
Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia
NCT01076569 ·Status: COMPLETED
-
Prognostic Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia
NCT01245231 ·Status: COMPLETED
-
Development and Application of a Novel Digital Array PCR for Acute Myeloid Leukemia (AML)
NCT04920188 ·Status: TERMINATED
-
Biomarkers in Bone Marrow and Blood Samples From Older Patients With Acute Myeloid Leukemia Treated With Cytarabine-Based Therapy
NCT01169363 ·Status: COMPLETED
-
Diagnostic Study of Gene Alterations in Patients With Acute Myeloid Leukemia
NCT00003931 ·Status: COMPLETED
-
Cytogenetic Studies in Acute Leukemia and Multiple Myeloma
NCT00048958 ·Status: ACTIVE_NOT_RECRUITING
-
Pilot Evaluation of a Microfluidic Assay to Detect Minimal Residual Disease and Predict Relapse in AML Patients
NCT03488862 ·Status: COMPLETED
-
Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia
NCT01801046 ·Status: TERMINATED ·Phase: PHASE1
-
Improving Risk Assessment of AML With a Precision Genomic Strategy to Assess Mutation Clearance
NCT02756962 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Leukemia Stem Cell Detection in Acute Myeloid Leukemia
NCT02927938 ·Status: TERMINATED ·Phase: PHASE3
-
Molecular Epidemiology of Acute Myelogenous Leukemia
NCT00502983 ·Status: UNKNOWN
-
Studying Samples From Patients With T-Cell Acute Lymphoblastic Leukemia
NCT01581528 ·Status: COMPLETED
-
Metabolic Changes in Blood Samples From Patients With Acute Myeloid Leukemia
NCT02581917 ·Status: COMPLETED
-
Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker
NCT07060001 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
AML Therapy With Irradiated Allogeneic Cells
NCT02105116 ·Status: TERMINATED ·Phase: NA
-
Autologous Bone Marrow Transplantation in Acute Non-Lymphoblastic Leukemia During First or Subsequent Remission
NCT00186381 ·Status: COMPLETED ·Phase: PHASE2
-
Risk-stratified Therapy Based on Molecular Cytogenetic Aberration and Treatment Response in AML
NCT03620955 ·Status: UNKNOWN
-
Determination of Epigenetic Markers of Acute Myeloblastic Leukemia in Elderly Patients
NCT07250217 ·Status: RECRUITING ·Phase: NA
-
Transfusion in Adult Acute Myeloid Leukemia
NCT02899767 ·Status: COMPLETED
-
Biomarkers in DNA Samples From Younger Patients With Newly Diagnosed Acute Myeloid Leukemia Receiving Gemtuzumab Ozogamicin
NCT01139320 ·Status: COMPLETED
-
Feasibility and Outcomes of Allogeneic HCT Compared to Chemotherapy in Older AML Patients
NCT01929408 ·Status: COMPLETED
-
Prognostic Values of Next Generation Sequencing (NGS) in Acute Myeloid Leukemia Patients With Allo-HSCT
NCT03715621 ·Status: UNKNOWN
-
Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML
NCT00568633 ·Status: TERMINATED ·Phase: PHASE3