HIV Prevention and Trauma Treatment for Men Who Have Sex With Men With Childhood Sexual Abuse Histories

Summary

Brief Summary: The specific aims of this study are:

1. To test, in a two-arm randomized controlled trial, the efficacy of cognitive processing therapy for sexual risk and posttraumatic symptom severity reduction (CPT-SR) in HIV-uninfected men who have sex with men (MSM) who have histories of childhood sexual abuse (CSA). The primary outcome is reduction in unprotected anal/vaginal intercourse (number and proportion) with serodiscordant partners. The investigators will also examine the intervention effect on CSA-related trauma symptom severity and cognitions and behaviors.
2. To examine the degree to which intervention-related reductions in sexual risk behavior are mediated by reductions in CSA-related symptom severity, cognitions, and behaviors.
3. To examine the degree to which the intervention reduces incident sexually transmitted infections (STIs) during the study period, as well as to explore additional potential moderators and mediators of intervention efficacy.

Study hypotheses:

1. For the primary outcome, the investigators hypothesize that those who receive the intervention will have reduced transmission-risk behavior.
2. For the secondary outcome, the investigators hypothesize that those who receive the intervention will have reduced trauma symptom severity (cognitions and behaviors).

Conditions

• Sexual Risk Behavior
• Childhood Sexual Abuse
• Stress Disorders, Post-Traumatic

Interventions

BEHAVIORAL

Cognitive Processing Therapy for Sexual Risk

Eight weekly sessions, 4 modules.

BEHAVIORAL

Supportive Psychotherapy

Eight weekly sessions

BEHAVIORAL

Sexual Risk Reduction Intervention

Two weekly sessions.

Sponsors & Collaborators

• Fenway Community Health

  collaborator OTHER

• University of Miami

  collaborator OTHER

• Massachusetts General Hospital

  lead OTHER

Principal Investigators

• Conall O'Cleirigh, Ph.D. · Massachusetts General Hospital

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

MALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-10-31

Primary Completion

2017-05-31

Completion

2017-05-31

Countries

• United States

Study Locations