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Relationship Between Cognitive Function and Pain

NCT01375348 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2012-02-14

No results posted yet for this study

Summary

Patients with chronic pain can experience considerable changes in their cognitive function such as forgetfulness, increased absentmindedness, confusion etc. Opioids (e.g. morphine and morphine-like analgesics) are often used in treatment of acute and chronic pain and can lead to worsening of the cognitive function. The interaction between pain, treatment and cognitive function is very complex and is far from understood.

The hypothesis of the present study is that by use of experimental pain in healthy volunteers it will be possible to elucidate the interaction between pain, treatment and cognitive function.

Conditions

  • Cognitive Ability, General

Interventions

DRUG

Ultiva (remifentanil) or placebo

0.1microg/kg/min remifentanil administered as infusion Max infusion time is 20min

Sponsors & Collaborators

  • Mech-Sense

    collaborator OTHER

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Asbjørn M Drewes, Professor · Mech-Sense

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-06-30
Primary Completion
2012-02-29
Completion
2012-02-29

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01375348 on ClinicalTrials.gov