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Effect of Bone on Vibration-Induced Muscle Electrical Activity

NCT01367041 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2013-01-30

No results posted yet for this study

Summary

The aim of this study is to investigate effects of femur exposed to vibration on the rest muscle electrical activity of hip adductors in cases with postmenopausal osteoporosis.

Among patients who will be admitted to the investigators clinic for out-patients and whose bone densitometric measurement will be made with a prediagnosis postmenopausal osteoporosis, a total of 80 voluntaries \[40 having postmenopausal osteoporosis (femur neck or total hip T score \< -2.0) and 40 Controls (Hip and lumbar bone mineral density normal)\] are planned to include in this study.

After the left hip bone mineral density (BMD) and BMC is measured in all cases, whole body vibration will be applied in PMO groups and Controls. The rest muscle electrical activity of left hip muscles will be evaluated at pre-treatment, post-treatment and, during treatment in patients with PMO and then their data will be compared with Controls data.

Plasma sclerostin level will be measured before and 10th minute after vibration.

Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 30 + 30 seconds. WBV will be applied one session only. The left hip BMD and BMC will be evaluated by bone densitometer (Norland).

The rest muscle electrical activity of hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.

This project is planed to be completed in 3 months.

Conditions

Interventions

PROCEDURE

vibration

Vibration frequency: 40 Hz, duration: 30+30 s, 2mm amplitude

Sponsors & Collaborators

  • Istanbul University

    collaborator OTHER

  • Bagcilar Training and Research Hospital

    lead OTHER_GOV

Principal Investigators

  • ILHAN KARACAN, MD · Bagcilar Training & Research Hospital

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-04-30
Primary Completion
2011-06-30
Completion
2011-07-31

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01367041 on ClinicalTrials.gov