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Effect of Ketamine on Postoperative Clinical Outcomes

NCT01365195 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2022-03-02

Study results available
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Summary

The purpose of this research is to evaluate the effectiveness of ketamine as an analgesic adjuvant in decreasing the narcotic (opioids) analgesics during surgery, on pain management and on the later recovery after surgery in patients undergoing colorectal surgery.

Conditions

  • Colorectal Surgery

Interventions

DRUG

Placebo

Loading and Infusion: Saline at infusion rate calculated and adjusted for weight to match ketamine bolus-infusion rate

DRUG

Ketamine high-dose

Loading: 1 mg/Kg Infusion: 10 mcg/kg/min

DRUG

Ketamine low-dose

Loading: 0.5 mg/Kg Infusion: 5 mcg/kg/min

Sponsors & Collaborators

  • Cedars-Sinai Medical Center

    lead OTHER

Principal Investigators

  • Roya Yumul, MD PhD · Cedars-Sinai Medical Center

  • Roya Yumul, MD., PhD · Cedars-Sinai Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-05-31
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01365195 on ClinicalTrials.gov