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Severe Sepsis/Septic Shock on Admission to the General Surgical ICU

NCT01363635 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 800

Last updated 2023-10-31

No results posted yet for this study

Summary

Severe sepsis/septic shock are serious complications of infection with high morbidity and mortality. Recent information showed that early and aggressive resuscitation may help improving survival and outcome especially the resuscitation within the first 3 hours. In surgical patients, either severe sepsis/septic shock bought them to the operating room or this sepsis might be found after surgery resulting in higher morbidity and mortality. Not only knowledge management, others possible risk factors should also be identified and corrected for outcome improving. This prospective observational study will be done in 800 adult surgical patients admitting to the general surgical intensive care unit. Incidence of severe sepsis/septic shock on admission along with risk factors associated with poor outcomes \[organ failure (AKI, ALI, PMI, liver failure, stroke), prolonged ICU length of, stay, ICU death\] will be recorded especially effect of amount and type of fluid replacement in the first 6 hours, 24, 48 and 72 hours after diagnosis. Outcome as major organ failure, ICU length of stay, ICU, 28 and 90 days mortality will also be study.

Conditions

  • Septic Shock
  • Multiple Organ Failure
  • Fatal Outcome

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Principal Investigators

  • Suneerat Kongsayreepong, MD · Siriraj Hospital, Mahidol University, Bnagkok, Thailand

Eligibility

Min Age
19 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-06-30
Primary Completion
2024-06-30
Completion
2024-06-30

Countries

  • Thailand

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01363635 on ClinicalTrials.gov