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Trial of Transcranial Direct Current Stimulation (tDCS)

NCT01346306 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2023-03-30

No results posted yet for this study

Summary

Among antidepressant treatments, ECT stands as the most effective in treating acute depression. However, patient concerns with the cognitive side effects of ECT have encouraged the development of new and more focal forms of brain stimulation such as transcranial Direct Current Stimulation (tDCS). However, not all patients may respond to this treatment in the way that it is currently administered and this has raised interest in finding alternative, possibly more optimal ways of administering tDCS. This study will investigate whether tDCS stimulation using an alternative electrode montage has antidepressant effects. Further sessions of tDCS, spaced less frequently, will be trialed for maintenance treatment. Mood, cognitive test performance and biomarkers will be measured periodically in the duration of the trial.

Conditions

Interventions

DEVICE

Eldith Company - direct current stimulator

Direct current stimulation montage 1.

DEVICE

Eldith Company - direct current stimulator

Direct current stimulation montage 2.

Sponsors & Collaborators

  • Singapore General Hospital

    collaborator OTHER

  • The University of New South Wales

    lead OTHER

Principal Investigators

  • Colleen Loo, MBBS, FRANZCP, MD · School of Psychiatry, University of New South Wales

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-04-30
Primary Completion
2019-12-23
Completion
2019-12-23

Countries

  • Australia
  • Singapore

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01346306 on ClinicalTrials.gov