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CO2 Absorption During Laparoscopy

NCT01340989 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2011-10-26

No results posted yet for this study

Summary

CO2 absorption from the pneumoperitoneum increases over time during laparoscopic procedures. Adding 4% of oxygen to the carbon dioxide was shown in rabbits to decrease CO2 resorbtion through prevention of mesothelial hypoxia. We want to prove this concept in human and expand it to the use of full conditioning.

Conditions

  • Pneumoperitoneum

Interventions

PROCEDURE

alteration of the insufflation gas

addition of 4% oxygen

PROCEDURE

full conditioning

addition of 4% oxygen + 10% nitrous oxide to the peritoneum * humidification * set temperature of 32°C

PROCEDURE

standard pneumoperitoneum

no intervention besides the use of CO2

Sponsors & Collaborators

  • University Hospital, Gasthuisberg

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-08-31
Primary Completion
2011-09-30
Completion
2011-09-30

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01340989 on ClinicalTrials.gov