Trial Outcomes & Findings for Rebreathing of Carbon Dioxide With a Device Used for Giving Inhalational Anaesthesia (NCT NCT01339013)

NCT ID: NCT01339013

Last Updated: 2014-09-25

Results Overview

A conventional heat and moisture exchanger used in a respiratory circuit during anasthesia was exchanged by an AnaConDa. The AnaConDa causes re-breathing of carbon dioxide which clinically is equivalent to an increased airway dead space. The total airway dead space effect of the AnaConDa, i.e. volume of the device plus rebreathing from the charcoal filter was measured using the Single Breath Test for carbon dioxide, as was airway deadspace of the conventional Heat and Moisture Exchanger. Airway dead space differences between devices was calculated by subtraction of volumes thus achieved. Difference= Airway dead space AnaConDa - Airway dead space conventional Heat and Moisture Exchanger.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

6 participants

Primary outcome timeframe

1 hour

Results posted on

2014-09-25

Participant Flow

September 2011 to January 2013, Medical Clinic

All recruited patients participated uneventfully.

Participant milestones

Participant milestones
Measure
AnaConDa Replaces the Heat and Moisture Exchanger
The conventional Heat and Moisture Exchanger is replaced by the AnaConDa which in turn is replaced by the conventional Heat and Moisture Exchanger.
Overall Study
STARTED
6
Overall Study
COMPLETED
6
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Rebreathing of Carbon Dioxide With a Device Used for Giving Inhalational Anaesthesia

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Study Participants
n=6 Participants
Heat and Moisture Exchanger, then AnaConDa, finally Heat and Moisture Exchanger
Age, Continuous
63 years
n=99 Participants
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
4 Participants
n=99 Participants
Age, Categorical
>=65 years
2 Participants
n=99 Participants
Sex: Female, Male
Female
1 Participants
n=99 Participants
Sex: Female, Male
Male
5 Participants
n=99 Participants
Region of Enrollment
Sweden
6 participants
n=99 Participants

PRIMARY outcome

Timeframe: 1 hour

A conventional heat and moisture exchanger used in a respiratory circuit during anasthesia was exchanged by an AnaConDa. The AnaConDa causes re-breathing of carbon dioxide which clinically is equivalent to an increased airway dead space. The total airway dead space effect of the AnaConDa, i.e. volume of the device plus rebreathing from the charcoal filter was measured using the Single Breath Test for carbon dioxide, as was airway deadspace of the conventional Heat and Moisture Exchanger. Airway dead space differences between devices was calculated by subtraction of volumes thus achieved. Difference= Airway dead space AnaConDa - Airway dead space conventional Heat and Moisture Exchanger.

Outcome measures

Outcome measures
Measure
AnaConDa
n=6 Participants
Anesthetic Conserving Device (AnaConDa) has a charcoal filter.
Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas.
136 mL
Interval 120.0 to 167.0

Adverse Events

AnaConDa

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr Louise Walther Sturesson

Region Skane, Lund University Hospital, Lund, Sweden

Phone: +46 46 171953

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place