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The Efficacy of Zoledronic Acid in Modic Changes-related Low Back Pain (LBP)

NCT01330238 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2014-01-15

No results posted yet for this study

Summary

Modic changes are associated with low back pain (LBP) both in clinical and general population-based samples. Type I changes are regarded as more likely to be painful than type II changes. Several studies suggest that type I changes are inflammatory in nature.

Conditions

  • Low Back Pain

Interventions

DRUG

Zoledronic acid vs. placebo

Single infusion of zoledronic acid or placebo

Sponsors & Collaborators

Principal Investigators

  • Jaro Karppinen, Prof · University of Oulu

  • Katri Koivisto, MD · University of Oulu

  • Eero Kyllönen, MD · University Hospital of Oulu

  • Kaj Sundqvist, MD · University Hospital of Oulu

  • Jaakko Niinimäki, MD · University of Oulu

  • Osmo Tervonen, Prof. · University of Oulu

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-12-31
Primary Completion
2011-03-31
Completion
2012-03-31

Countries

  • Finland

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01330238 on ClinicalTrials.gov