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Optimal Surgery and MRI Based Radiochemotherapy in Rectal Carcinoma

NCT01325649 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1051

Last updated 2016-10-19

No results posted yet for this study

Summary

The objective of the study is to provide proof that a MRI based preoperative radiochemotherapy in patients with locally advanced rectal carcinoma allows limiting RCT to high risk patients without increase of locoregional recurrence rate and decrease of overall survival provided there is a high quality of mesorectal excision.

Conditions

  • Rectal Cancer Stage II
  • Rectal Cancer Stage III

Interventions

PROCEDURE

total mesorectal excision / long course radiochemotherapy

long course 5-FU based radiochemotherapy before total mesorectal excision

RADIATION

long course 5-FU bases radiochemotherapy

Sponsors & Collaborators

  • Johannes Gutenberg University Mainz

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-02-28
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01325649 on ClinicalTrials.gov