Resveratrol With or Without Piperine to Enhance Plasma Levels of Resveratrol
NCT01324089 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2019-12-13
Summary
There is some evidence that when resveratrol (a substance which is found in red grapes, peanuts and chocolate) is combined with Piperine (a substance found in pepper) it is more effective in fighting cancer. The purpose of this study is to see if resveratrol in combination with piperine is more effective than taking resveratrol alone. Since investigators don't know what dose of piperine to use in combination with resveratrol, two different doses of piperine will be studied.
Twenty-four participants, equal numbers of males and females, will receive a single dose of resveratrol (2.5 grams) without piperine, resveratrol (2.5 grams) with piperine (5 mg), or resveratrol (2.5 grams) with piperine (25 mg).
Conditions
- Focus of the Study: Normal Volunteers
Interventions
- DIETARY_SUPPLEMENT
-
Resveratrol
Resveratrol 2.5 grams
- DIETARY_SUPPLEMENT
-
Resveratrol 2.5 grams x 1 dose and Piperine 5 mg x 1 dose
Resveratrol 2.5 grams x 1 dose and Piperine 5 mg x 1 dose
- DIETARY_SUPPLEMENT
-
Resveratrol 2.5 grams x 1 dose and Piperine 25 mg x 1 dose
Resveratrol 2.5 grams x 1 dose and Piperine 25 mg x 1 dose
Sponsors & Collaborators
-
National Institutes of Health (NIH)
collaborator NIH -
National Cancer Institute (NCI)
collaborator NIH -
University of Wisconsin, Madison
lead OTHER
Principal Investigators
-
Howard H Bailey, MD · University of Wisconsin, Madison
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-03-31
- Primary Completion
- 2011-11-30
- Completion
- 2012-03-31
Countries
- United States
Study Locations
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