Trial Outcomes & Findings for Measurement of Kidney Blood Flow and Oxygen Levels by MRI (NCT NCT01318967)
NCT ID: NCT01318967
Last Updated: 2018-09-07
Results Overview
Renal blood flow is estimated by the PAH method.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
10 participants
Primary outcome timeframe
Renal blood flow is estimated over 1 hour by PAH
Results posted on
2018-09-07
Participant Flow
Participant milestones
| Measure |
Furosemide
With and without furosemide
Furosemide: Renal blood flow is measured before and after the administration of 20 mg of furosemide.
|
|---|---|
|
Overall Study
STARTED
|
10
|
|
Overall Study
COMPLETED
|
10
|
|
Overall Study
NOT COMPLETED
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Measurement of Kidney Blood Flow and Oxygen Levels by MRI
Baseline characteristics by cohort
| Measure |
Furosemide
n=10 Participants
With and without furosemide
Furosemide: Renal blood flow is measured before and after the administration of 20 mg of furosemide.
|
|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=99 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
8 Participants
n=99 Participants
|
|
Age, Categorical
>=65 years
|
2 Participants
n=99 Participants
|
|
Sex: Female, Male
Female
|
6 Participants
n=99 Participants
|
|
Sex: Female, Male
Male
|
4 Participants
n=99 Participants
|
|
Region of Enrollment
United States
|
10 participants
n=99 Participants
|
PRIMARY outcome
Timeframe: Renal blood flow is estimated over 1 hour by PAHRenal blood flow is estimated by the PAH method.
Outcome measures
| Measure |
Furosemide
n=10 Participants
With and without furosemide
Furosemide: Renal blood flow is measured before and after the administration of 20 mg of furosemide.
Renal blood flow is measured by PAH method and by MRI method
|
|---|---|
|
Measurement of Renal Blood Flow of the Kidney by the PAH Method
|
190 ml/min
Interval 47.0 to 342.0
|
SECONDARY outcome
Timeframe: One measure after furosemide (day 1)Estimate of renal blood flow by using MRI scans before and after the administration of furosemide
Outcome measures
| Measure |
Furosemide
n=10 Participants
With and without furosemide
Furosemide: Renal blood flow is measured before and after the administration of 20 mg of furosemide.
Renal blood flow is measured by PAH method and by MRI method
|
|---|---|
|
Measurement of Regional Blood Oxygenation by MRI
|
300 ml/min
Interval 69.0 to 620.0
|
Adverse Events
Furosemide
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place