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The Natural History of Small Renal Masses

NCT01305330 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 137

Last updated 2020-09-10

No results posted yet for this study

Summary

There is a rising incidence of incidentally detected small renal tumours due to improved imaging techniques. Traditionally, patients diagnosed with these small renal masses undergo surgery and therefore there is limited data about the natural history of these tumours. Several small series have reported that most of these small masses grow slowly and might not require early intervention and that only some masses grow rapidly requiring immediate surgery. Presently, the investigators have not been able to identify prospectively which masses are going to grow slowly. The investigators plan to use computed tomography (CT) and Magnetic Resonance Imaging (MRI) parameters, microsatellite analysis and tissue analysis to determine which masses will behave more aggressively. Additionally, the observations on the natural history of small renal masses need to be validated with a multicentric and systematically followed cohort.

Conditions

  • Patients With Newly Diagnosed Small Renal Masses(<4cm)

Sponsors & Collaborators

  • The Kidney Foundation of Canada

    collaborator OTHER

  • Canadian Urologic Oncology Group

    collaborator OTHER

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Michael AS Jewett, MD, FRCSC · University Health Network, Princess Margaret Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-08-31
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01305330 on ClinicalTrials.gov