Canakinumab for Pyoderma Gangrenosum
NCT01302795 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 5
Last updated 2016-09-27
Summary
This study is a prospective open label evaluation of Canakinumab (Ilaris) for treatment of subjects with pyoderma gangrenosum.
Conditions
- Pyoderma Gangrenosum
Interventions
- DRUG
-
Canakinumab
Monoclonal antibody inhibiting interleukin 1 beta
Sponsors & Collaborators
-
University of Zurich
lead OTHER
Principal Investigators
-
Lars French, Prof MD · University Hospital Zurich, Division of Dermatology
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-02-28
- Primary Completion
- 2014-08-31
- Completion
- 2015-11-30
Countries
- Switzerland
Study Locations
More Related Trials
-
The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis
NCT00794274 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Riociguat in Scleroderma Associated Digital Ulcers
NCT02915835 ·Status: COMPLETED ·Phase: PHASE2
-
Topical Sirolimus for the Treatment of Pachyonychia Congenita (PC)
NCT02152007 ·Status: COMPLETED ·Phase: PHASE1
-
INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa
NCT04908215 ·Status: COMPLETED ·Phase: PHASE2
-
Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study
NCT02960997 ·Status: COMPLETED ·Phase: PHASE2
-
Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement
NCT00573326 ·Status: UNKNOWN ·Phase: PHASE2
-
A Protocol Based Treatment for Debilitating Fibrosing Skin Disorders With (Anti-CD 20), Rituximab, Evaluating Safety and Efficacy
NCT00936546 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis Pemphigus
NCT01313923 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Study on the Clinical Features, Comorbidities and Pathologies Associated With Pyoderma Gangrenosum
NCT03636737 ·Status: UNKNOWN
-
Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis
NCT02921971 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation and Treatment of Patients With Dermatologic Diseases
NCT00001506 ·Status: COMPLETED
-
Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host Disease
NCT01309997 ·Status: COMPLETED ·Phase: PHASE2
-
Profibrosing Role of B Lymphocytes in Patients With Systemic Sclerosis.
NCT03559465 ·Status: COMPLETED ·Phase: NA
-
Early and Long-Term Efficacy and Immune Changes With Dupilumab in Prurigo Nodularis
NCT07276425 ·Status: RECRUITING
-
Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study
NCT03016715 ·Status: UNKNOWN ·Phase: PHASE2
-
Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome.
NCT04904146 ·Status: RECRUITING
-
Clinical Characteristics of Pruritus and Evaluation of Quality of Life in Patients With Bullous Pemphigoid
NCT03272958 ·Status: COMPLETED
-
A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis
NCT02161406 ·Status: COMPLETED ·Phase: PHASE2
-
Sildenafil for Treatment of Digital Ulcers in Patients With Systemic Sclerosis
NCT00624273 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Study of Tranilast in the Treatment of Sarcoidosis
NCT03528070 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis
NCT00043706 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Generation of Powerful Biological Tools for Understanding the Pathophysiology of Chronic Granulomatous Disease.
NCT02926963 ·Status: TERMINATED ·Phase: NA
-
Stem Cell Factor, a Potential Biological Marker of Skin Involvement in Systemic Sclerosis?
NCT05482594 ·Status: UNKNOWN
-
Hidradenitis Suppurativa Prospective Observational Registry and Biospecimen Repository
NCT04115566 ·Status: RECRUITING
-
EN3835 for the Treatment of Edematous Fibrosclerotic Panniculopathy (Commonly Known as Cellulite)
NCT02942160 ·Status: COMPLETED ·Phase: PHASE2