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Effect of an Anti-inflammatory on Tooth Sensitivity Caused by Bleaching

NCT01300780 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2017-08-18

No results posted yet for this study

Summary

Perhaps the use of a more selective anti-inflammatory drug, capable of inhibiting enzyme specific for pain may be more effective in preventing the tooth sensitivity caused by the inflammatory response produced by in-office bleaching. To the extent of the authors´ knowledge, no study has so far addressed the use of a selective anti-inflammatory drug specific for pain enzyme on tooth sensitivity, being this the aim of the present investigation.

Conditions

  • Color Changes During Tooth Formation

Interventions

DRUG

Etoricoxib

Group 2 - experimental Etoricoxib will receive two doses of selective anti-inflammatory to enzyme cyclooxygenase 2 (COX-2) (Etoricoxib 60 mg) given once every 24 hours;

OTHER

Placebo

Group 1 - Control Group will receive two doses of placebo tablet administered a every 8 hours,

Sponsors & Collaborators

  • Universidade Estadual de Ponta Grossa

    collaborator OTHER

  • Fundação Araucária

    collaborator OTHER

  • Eloisa Andrade de Paula

    lead OTHER

Principal Investigators

  • Alessandra Reis, doctor · Universidade Estadual de Ponta Grossa

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-04-30
Primary Completion
2011-09-30
Completion
2011-11-30

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01300780 on ClinicalTrials.gov