Esophageal High Resolution Manometry and Dysphagia

Summary

Two to 15% of subjects present dysphagia. In case of normal eso-gastro-duodenal endoscopy, patients with dysphagia are referred for esophageal motility testing. Esophageal manometry is the gold standard to evaluate esophageal motility in absence of esophageal obstruction. Two different techniques are available: the conventional manometry and the high resolution manometry. The second one may improve the diagnostic yield and the tolerance of examination in patients with dysphagia.

Conditions

• Dysphagia

Interventions

DEVICE

Conventional manometry

Conventional esophageal manometry

DEVICE

High resolution manometry

High resolution esophageal manometry

Sponsors & Collaborators

• Hospices Civils de Lyon

  lead OTHER

Principal Investigators

• Sabine ROMAN, Dr · Unité d'Exploration Fonctionnelle Digestive - Hôpital Edouard Herriot - 69437 Lyon Cedex 03- France

• Stanislas BRULEY DES VARANNES · Service d'Hépato-Gastro-Entérologie - CHU Hôtel Dieu - Place A Ricordeau - 44093 Nantes Cedex - France

• Franck ZERBIB · Service d'Hépato-Gastro-Entérologie - Hôpital Saint-André - 33075 Bordeaux Cedex - France

• Guillaume GOURCEROL · Service de Physiologie Digestive, Respiratoire, Urinaire et Sportive - CHU de Rouen - 76031 Rouen Cedex - France

• Silvana PERRETTA · Pole Hépato- Digestif, Service de Chirurgie digestive et endocrinienne - Nouvel Hôpital Civil - 1 place de l'Hôpital - 67091 Strasbourg cedex - France

• Franck ROPERT · Service d'Hépato-Gastro-Entérologie - CHU Pontchaillou - Rue H. le Guillou - 35033 Rennes cedex - France

• François MION, MD · Service d'Hépato-Gastro-Entérologie, Hôpital de la Croix-Rousse , 69317 Lyon

• Benoit COFFIN, MD · Service d'Hépato-Gastroentérologie, Hôpital Louis Mourier, 92700 Colombes

Study Design

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-02-28

Primary Completion

2013-12-31

Completion

2013-12-31

Countries

• France

Study Locations