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Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus

NCT01281618 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2013-05-06

No results posted yet for this study

Summary

The purpose of this study is to determine the association between acid reflux and cell changes in Barrett's esophagus.

Specific aim 1: To test the hypothesis that controlled acid reflux is associated with lesser degree of stromal activation.

Specific aim 2: To test the hypothesis that stromal fibroblast derived growth factors drive BE epithelial proliferation.

Conditions

  • Barrett's Esophagus

Interventions

PROCEDURE

24 hour pH study and upper endoscopy (EGD)

All subjects enrolled will undergo 24 hour pH followed by EGD.

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • Mayo Clinic

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-10-31
Primary Completion
2011-06-30
Completion
2011-06-30

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01281618 on ClinicalTrials.gov