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Effects of Osteotomies Around the Knee on Cartilage Glycosaminoglycan Content Using dGEMRIC Non-invasive Imaging

NCT01269944 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2017-11-06

No results posted yet for this study

Summary

Medial compartment osteoarthritis of the knee is commonly treated by a surgical intervention called 'high tibial osteotomy' (VTO). Although it has repeatedly been shown that pain improves following this procedure, it is unknown how cartilage quality is affected by the procedure. In this study, a recently developed MRI technique is used to evaluate changes in cartilage quality before and after the surgery. Changes in MRI signals are correlated to subjective improvements (score lists). 10 patients participate in this study. Approval has been granted by the Medical Ethical Committee of the University Medical Center Utrecht. All participants are required to give informed consent before participation.

Conditions

  • Medial Compartment Osteoarthritis of the Knee

Sponsors & Collaborators

  • UMC Utrecht

    lead OTHER

Principal Investigators

  • Daniel B Saris, MD, PhD · University Medical Center Utrecht, the Netherlands

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-07-31
Primary Completion
2011-02-28
Completion
2011-02-28

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01269944 on ClinicalTrials.gov