MedTrace Logo

The Influence of Chinese Medicine on Metabolomics in Menopausal or Postpartum Women

NCT01264068 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2010-12-21

No results posted yet for this study

Summary

Traditional Chinese herbal medicine, no matter mono-therapy or poly-pharmacy, is composed of complicated chemical constituents. Many confounding factors influence activity of Chinese herbs, including the origin of the herbs, safety of the products and consistency between batches. Study of the effectiveness and mechanism of Chinese herbs in vivo is much more challengeable due to unresolved problems of product quality control, screen of effective principles, monitor of the marker constituents and the targets for site of action. In this project, we will introduce the concept of metabolomics to detect total metabolites spectra as the biomarkers of Chinese herbs intervention. Correlation will be analyzed between changes in total metabolites and clinical improvements when menopausal women receive Suan Tsao Jen Tang or Jia Wey Shiau Yau San, and postpartum women receive生化湯.

Conditions

  • Menopausal Women

Interventions

DRUG

Finished Herbal Product such as Suan Tsao Jen Tang, Jia-Wey Shiau-Yau San

Take medicine every day 3 times, each time 4 grams.

Sponsors & Collaborators

  • National Taiwan University Hospital

    collaborator OTHER

  • Taipei City Hospital

    lead OTHER_GOV

Principal Investigators

  • Yen-Hui Chen, PHD · Associate Professor, School of Pharmacy,National Taiwan University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-08-31
Primary Completion
2009-04-30
Completion
2009-12-31

Countries

  • Taiwan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01264068 on ClinicalTrials.gov