Expression of Optic Atrophy Type 1 (OPA1) Protein in Lung Adenocarcinoma
NCT01249053 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2010-11-29
Summary
Optic atrophy type 1(OPA1) is a nuclear dynamin-related GTPase, targeted to the inner mitochondrial membrane, which plays a role in mitochondrial fusion. Mitochondria fusion is associated with process of apoptosis. . OPA1 plays an important role in the mitochondrial bioenergetics and mitochondrial networks. The changes in mitochondrial shape and mitochondrial bioenergetics may be cause of the disease. In this study, we investigate the expression of OPA1 in lung adenocarcinoma (LADC) cells and tissue.
Conditions
Sponsors & Collaborators
-
China Medical University Hospital
lead OTHER
Eligibility
- Min Age
- 25 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-08-31
Countries
- Taiwan
Study Locations
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