MIBG Scintigraphy and Strain Echocardiography in the Detection of Subclinical Cardiovascular Effects One Year After (Neo)Adjuvant Breast Cancer Treatment With Docetaxel, Doxorubicin and Cyclophosphamide (TAC): a Pilot Study
NCT01246856 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2011-09-12
Summary
Many patients with breastcancer in the past, were treated with TAC. These last years, there is more and more focus on the effects of chemotherapy, particularly in children treated with this. One of these effects is damage to the heart muscle, which ultimately might affect the pump-function of the heart . In adults, the effect of treatment with TAC on the heart, has not been previously investigated. The possibility exists that the adverse reactions in children are found in adults also could occur. Therefore we have initiated this trial.
Conditions
Sponsors & Collaborators
-
Radboud University Medical Center
lead OTHER
Principal Investigators
-
H.W.M. van Laarhoven, Md · University Medical Centre Nijmegen
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-11-30
- Primary Completion
- 2011-10-31
Countries
- Netherlands
Study Locations
More Related Trials
-
Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients
NCT05732051 ·Status: RECRUITING ·Phase: PHASE2
-
Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy
NCT04305613 ·Status: ACTIVE_NOT_RECRUITING
-
Genetics and Heart Health After Cancer Therapy
NCT03510689 ·Status: COMPLETED
-
Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab
NCT00875238 ·Status: COMPLETED
-
Impact of Exercise on Mitigating the Cardio-toxic Effects of Adriamycin Among Women Newly Diagnosed With Breast Cancer.
NCT03027063 ·Status: COMPLETED ·Phase: NA
-
Early Detection of Heart Problems in Cancer Patients Receiving Chemotherapy
NCT04413487 ·Status: WITHDRAWN
-
Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery
NCT00436566 ·Status: COMPLETED ·Phase: PHASE2
-
CARdiac Function Evaluation in Breast Cancer Patients
NCT03266809 ·Status: COMPLETED
-
Acute Exercise Cardioprotection From Doxorubicin
NCT02006979 ·Status: COMPLETED ·Phase: PHASE1
-
Early Cardiac Toxicity of Adjuvant CT in Elderly BC.
NCT01301040 ·Status: TERMINATED ·Phase: PHASE2
-
Reporting, Evaluating, Preventing and Treating the Cardiotoxicity Induced by Anticancer Drugs During a Specific Cardio-oncology Consult and Follow up in Routine Care
NCT03882580 ·Status: UNKNOWN
-
Diagnosis and Prediction of Taxanes Induced Cardiac Dysfunction
NCT01641562 ·Status: COMPLETED
-
Cardiac Toxicity in Medical Treatment of Breast Cancer
NCT02440620 ·Status: COMPLETED
-
Prevention of Cardiac Dysfunction During Breast Cancer Therapy
NCT03760588 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Concomitant Radiotherapy and Trastuzumab on Cardiotoxicity of Patients Treated for Early Breast Cancer
NCT01572883 ·Status: COMPLETED
-
Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses
NCT04568161 ·Status: COMPLETED ·Phase: NA
-
Combination Chemotherapy in Treating Women With Stage IIIB or Stage IV Breast Cancer
NCT00003352 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel + Doxorubicin as Neoadjuvant Chemotherapy in Patients With Breast Cancer
NCT00461344 ·Status: TERMINATED ·Phase: PHASE2
-
BreAst Cancer and Cardiotoxicity Induced by RAdioTherapy: the BACCARAT Study
NCT02605512 ·Status: COMPLETED ·Phase: NA
-
Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer
NCT05078190 ·Status: ACTIVE_NOT_RECRUITING
-
Pilot Study of the Safety & Efficacy of Two Docetaxel-Based Regimens Plus Bevacizumab for the Adjuvant Treatment of Subjects With Node Positive or High Risk Node Negative Breast Cancer
NCT00446030 ·Status: COMPLETED ·Phase: PHASE2
-
A Pharmacogenomics Study for Breast Cancer Patients Undergoing Adjuvant Chemotherapy With Doxorubicin (A)/Cyclophosphamide ©) and/or Weekly Paclitaxel
NCT00131963 ·Status: COMPLETED
-
Neo-Adjuvant Chemotherapy (TAC) With or Without Zoledronic Acid in Treating HER2-negative Breast Cancer Patients
NCT01099436 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Heart Function in Breast Cancer Patients Using Trastuzumab
NCT04961307 ·Status: UNKNOWN
-
Cyclophosphamide and Docetaxel Every 3 Weeks as Neoadjuvant Therapy in Locally Advanced Breast Cancer
NCT01229605 ·Status: WITHDRAWN ·Phase: PHASE2