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Effects of Prednisolone and Pentoxifylline on the Regulation of Urea Synthesis in Alcoholic Hepatitis

NCT01245257 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2016-09-12

No results posted yet for this study

Summary

Loss of total mass of muscles (catabolism) is a serious clinical problem in patients with alcoholic hepatitis. The liver might play an important role in this stress-catabolism by increasing the production of urea during the inflammatory process.

The purpose of this study is to examine the regulation of urea synthesis in patients with alcoholic hepatitis and to study the effect of the anti-inflammatory drugs prednisolone and pentoxifylline on this regulation.

Conditions

  • Alcoholic Hepatitis

Sponsors & Collaborators

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Karen Louise Thomsen, MD · Aarhus University Hospital

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-11-30
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01245257 on ClinicalTrials.gov