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Persistent Pulmonary Artery Hypertension After Valve Replacement

NCT01238731 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2010-11-11

No results posted yet for this study

Summary

Background: Persistent severe pulmonary hypertension (PH) after mechanical valve replacement is a frequent finding in patients with severe valve-diseases. The reasons to develop PH are multifactorial and the prevalence of severe PH significantly worsens the patients´ outcome.

Aims: (i) To define the prevalence of PH in patients after valve replacement and (ii) to identify factors predicting persistent PH.

Methods: All patients which underwent valve replacement at our institution between the years 2008 -2010 will be screened retrospectively. Those patients with pre- procedural proven PH by means of right-heart catheterization will receive prospective follow-up with echocardiography. Diagnosis of persistent PH will be confirmed with right heart catheterization.

Conditions

  • Persistent Severe PH After Valve Therapy

Sponsors & Collaborators

  • Actelion Pharmaceuticals Deutschland GmbH

    collaborator INDUSTRY

  • University Hospital, Bonn

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2011-01-31
Completion
2012-03-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01238731 on ClinicalTrials.gov