Smoking Abstinence and Lapse Effects in Smokers With Schizophrenia and Controls
NCT01214005 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2012-04-27
Summary
This project tests two hypotheses concerning the low smoking cessation rates in smokers with schizophrenia. The first hypothesis is that smokers with schizophrenia experience stronger and more sustained effects of smoking abstinence on negative mood and smoking urge than control smokers without psychiatric illness. The second hypothesis is that smokers with schizophrenia experience stronger reinforcing effects of a smoking lapse (i.e., more rewarding effects of smoking after a period of abstinence) than control smokers without psychiatric illness.
Conditions
- Tobacco Use Disorder
- Schizophrenia
Interventions
- BEHAVIORAL
-
smoking abstinence
3 days of biologically-confirmed smoking abstinence
Sponsors & Collaborators
-
Brown University
lead OTHER
Principal Investigators
-
Jennifer Tidey, Ph.D. · Brown University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-06-30
- Primary Completion
- 2012-02-29
- Completion
- 2012-02-29
Countries
- United States
Study Locations
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