Hypoxia-guided Radiotherapy With Cisplatin-etoposide in Stage I-III : Small Cell Lung Cancer(SCLC)
NCT01210131 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2013-08-27
Summary
Since radiation dose escalation to a large volume of tumour inevitably will induce higher toxicity than is currently the case, efforts must be made to limit the volume of tissue irradiated. Moreover, the irradiation of larger tumour volumes leads to a lower achievable tumour dose when keeping the normal tissue doses constant. Central is thus the question whether it would be possible to limit the volume of tumour to be boosted by selectively escalating the radiation dose to specific disease sites which are theoretically more prone to relapse.
Conditions
- Small Cell Lung Cancer (SCLC)
Interventions
- DRUG
-
[18F]HX4
Intravenous injection
Sponsors & Collaborators
-
Maastricht University Medical Center
collaborator OTHER -
Maastricht Radiation Oncology
lead OTHER
Principal Investigators
-
Dirk De Ruysscher, MD, PhD · Maastro Clinic, The Netherlands
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-07-31
- Primary Completion
- 2014-01-31
- Completion
- 2014-08-31
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