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Can Dormant Perimenopausal Ovarian Follicles Become FSH Responsive?

NCT01201226 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2010-09-14

No results posted yet for this study

Summary

The purpose of this study to obtain ovarian cortical fragments from perimenopausal patients, who undergo pelvic organ surgery and test whether treatment with PTEN inhibitor and PI3K activating peptide would induce these fragments to produce FSH responsive follicles in the nude mouse model.

Conditions

  • Low Ovarian Reserve
  • Poor Responders to Gonadotropihins Treatment

Interventions

OTHER

Removal of half an ovary

Removal of half an ovary

Sponsors & Collaborators

  • The Baruch Padeh Medical Center, Poriya

    lead OTHER_GOV

Principal Investigators

  • Izhar Ben-Shlomo, MD · Dept. Ob/Gyn, Baruch Padeh Medical Center, Poria, Israel

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
45 Years
Max Age
51 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-11-30
Primary Completion
2011-11-30
Completion
2011-11-30

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01201226 on ClinicalTrials.gov