Study of Factors Predicting Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma (HCC)
NCT01198704 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 372
Last updated 2020-11-20
Summary
Results of liver transplantation, the best theoretical treatment for HCC, are limited by tumor recurrence. In order to limit this risk Milan criteria was proposed in 1996. However, these criteria are to restrictive and approximately 40% of patients denied by Milan criteria may be cured by liver transplantation.
The purpose of this study was thus to prospectively evaluate factors predicting tumor recurrence after liver transplantation for HCC and then to reassess criteria for liver transplantation.
Conditions
- Hepatocellular Carcinoma
- Liver Cirrhosis
- Evidence of Liver Transplantation
Interventions
- OTHER
-
search of factors predicting tumor recurrence
Morphological, chronological, anatomy-pathological and molecular search
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Thomas Decaens, MD, PhD · University Hospital, Grenoble
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-01-31
- Primary Completion
- 2017-01-31
- Completion
- 2020-01-31
Countries
- France
Study Locations
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