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Acute Lung Injury After Aortic Valve Surgery

NCT01184313 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2010-09-03

No results posted yet for this study

Summary

The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery.

Study questions:

* Is there any correlation between the release of pro-inflammatory biomarkers and lung injury degree?
* Is there any correlation between oxyhaemodynamic parameters and lung injury degree?
* Is there any correlation between oxyhaemodynamic parameters and the release of pro-inflammatory biomarkers?
* Are budesonide, erdostein and acetylcystein effective in the prevention of lung injuries?

Conditions

  • Lung Injury

Interventions

PROCEDURE

aortic valve surgery with CPB

elective aortic valve surgery with CPB

Sponsors & Collaborators

  • University of Oulu

    lead OTHER

Principal Investigators

  • Reija Mikkola, MS · Oulu University Hospital

  • Fausto Biancari, MD, PhD · Oulu University Hospital

  • Juha Koskenkari, MD · Oulu University Hospital

  • Vesa Pakanen, MD · Oulu University Hospital

  • Tatu Juvonen, prof. · Oulu University Hospital

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-09-30

Countries

  • Finland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01184313 on ClinicalTrials.gov