MedTrace Logo

ChloraPrep Versus Betadine for Elective Knee Replacement Surgery

NCT01184196 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2013-04-16

No results posted yet for this study

Summary

This study will enroll patients who will be receiving primary total knee replacements. Subjects will be randomized into two groups: Betadine surgical scrub preparation and ChloraPrep preparation prior to total knee replacements.

Study hypothesis: When used as a surgical scrub preparation prior to primary total knee arthroplasties, ChloraPrep (2% chlorhexadine gluconate and 70% isopropyl alcohol) is superior to Betadine (10% povidone iodine) in reducing incision site bacterial colony counts.

Conditions

  • Arthroplasty, Knee Replacement
  • Replacement, Total Knee
  • Total Knee Replacement

Interventions

DRUG

Swab area with Betadine

A swab will be taken over the operative knee before surgical site preparation is started, after preparation has taken place, and 24 hours post-surgery.

DRUG

Swab area with ChloraPrep

A swab will be taken over the operative knee before surgical site preparation is started, after preparation has taken place, and 24 hours post-surgery.

Sponsors & Collaborators

  • Central DuPage Hospital

    lead OTHER

Principal Investigators

  • Scott Sporer, MD · Midwest Orthopaedics at Rush

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-11-30
Primary Completion
2012-12-31
Completion
2012-12-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01184196 on ClinicalTrials.gov