Study of Panitumumab in the Treatment of Carcinoid Syndrome
NCT01172717 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-07-26
Summary
The primary hypothesis of this study is that panitumumab, an inhibitor of the epidermal growth factor receptor (EGFR), is an effective treatment for carcinoid syndrome in people who fail or do not adequately respond to octreotide or other supportive therapies.
Conditions
- Carcinoid Syndrome
Interventions
- DRUG
-
Panitumumab
Panitumumab will be given by intravenous infusion at a dose of 9 mg/kg on day 1 of study and then every 3 weeks until progression of disease
Sponsors & Collaborators
- collaborator INDUSTRY
-
Boston Medical Center
lead OTHER
Principal Investigators
-
Kevan Hartshorn, MD · Boston Medical Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-07-31
- Primary Completion
- 2013-07-31
- Completion
- 2013-07-31
Countries
- United States
Study Locations
More Related Trials
-
Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease
NCT03516279 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Testing the Safety and Efficacy of the Combination of the Antibody Pembrolizumab and Entinostat in Patients With Myelodysplastic Syndrome Who Are Not Responding to Hypomethylating Agents
NCT02936752 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy Study of PD-616 Plus Cytarabine to Treat Acute Myelogenous Leukemia or Myelodysplastic Syndrome
NCT01795924 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia
NCT03263572 ·Status: RECRUITING ·Phase: PHASE2
-
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome
NCT01463046 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia
NCT00006127 ·Status: UNKNOWN ·Phase: PHASE1
-
IGF-MTX Conjugate in the Treatment of Myelodysplastic Syndrome
NCT03175978 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Phase I Trial of Cabozantinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia
NCT01961765 ·Status: COMPLETED ·Phase: PHASE1
-
Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms
NCT05549661 ·Status: RECRUITING ·Phase: PHASE1
-
CPI-613 in Treating Patients With Myelodysplastic Syndromes Who Failed Previous Therapy
NCT01902381 ·Status: TERMINATED ·Phase: PHASE2
-
Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia
NCT02807272 ·Status: COMPLETED ·Phase: PHASE2
-
Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia
NCT01670084 ·Status: WITHDRAWN ·Phase: PHASE2
-
The Role of Erlotinib an Epidermal Growth Factor Receptor (EGFR) Inhibitor in the Treatment of Myelodysplastic Syndrome
NCT00570375 ·Status: WITHDRAWN ·Phase: PHASE2
-
KRT-232 and TKI Study in Chronic Myeloid Leukemia
NCT04835584 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors
NCT02403271 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Blinatumomab & Pembrolizumab for Adults With Relapsed/Refractory B-cell ALL With High Marrow Lymphoblasts
NCT03160079 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase II Nilotinib With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML)
NCT00129740 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Of Two Inotuzumab Ozogamicin Doses in Relapsed/ Refractory Acute Lymphoblastic Leukemia Transplant Eligible Patients
NCT03677596 ·Status: COMPLETED ·Phase: PHASE4
-
A Study Comparing Ponatinib and Nilotinib in Participants With Chronic Myeloid Leukemia
NCT02627677 ·Status: TERMINATED ·Phase: PHASE3
-
A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia
NCT04239157 ·Status: RECRUITING ·Phase: PHASE2
-
Ofatumumab and Dinaciclib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-Cell Prolymphocytic Leukemia
NCT01515176 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
NCT01383447 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study to Determine Safety, Feasibility and Efficacy of JCAR015 in Adult Subjects With B-Cell Acute Lymphoblastic Leukemia
NCT02973191 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Tipifarnib in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
NCT00027872 ·Status: COMPLETED ·Phase: PHASE2
-
Study of BGB-11417 in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT05479994 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2