Trial Outcomes & Findings for Evaluation of Treatments for Homeless Youths (NCT NCT01143792)

NCT ID: NCT01143792

Last Updated: 2013-04-16

Results Overview

Percentage of substance use days in prior three months.

Recruitment status

COMPLETED

Study phase

PHASE2

Target enrollment

270 participants

Primary outcome timeframe

Three months

Results posted on

2013-04-16

Participant Flow

recruitment ended on time, recruitment completed as proposed.

intent to treat design used.

Participant milestones

Participant milestones
Measure
CRA + HIV Prevention
Description of CRA: Treatment included twelve 1-hour sessions in addition to two HIV prevention sessions.
MET + HIV Prevention
Description of MET: Treatment included two 1-hour sessions in addition to two HIV prevention sessions.
Case Management + HIV Prevention
Description of CM: Treatment included twelve 1-hour sessions in addition to two HIV prevention sessions.
Overall Study
STARTED
93
86
91
Overall Study
COMPLETED
93
86
91
Overall Study
NOT COMPLETED
0
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Evaluation of Treatments for Homeless Youths

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
CRA + HIV Prevention
n=93 Participants
Treatment included twelve 1-hour sessions for a total of 14 sessions.
MET + HIV Prevention
n=86 Participants
Treatment included two 1-hour MI sessions for a total of 4 sessions
Case Management + HIV Prevention
n=91 Participants
Treatment included twelve 1-hour sessions for a total of 14 sessions.
Total
n=270 Participants
Total of all reporting groups
Age, Categorical
<=18 years
17 Participants
n=99 Participants
16 Participants
n=107 Participants
10 Participants
n=206 Participants
43 Participants
n=7 Participants
Age, Categorical
Between 18 and 65 years
76 Participants
n=99 Participants
70 Participants
n=107 Participants
81 Participants
n=206 Participants
227 Participants
n=7 Participants
Age, Categorical
>=65 years
0 Participants
n=99 Participants
0 Participants
n=107 Participants
0 Participants
n=206 Participants
0 Participants
n=7 Participants
Age Continuous
18.70 years
STANDARD_DEVIATION 1.34 • n=99 Participants
18.69 years
STANDARD_DEVIATION 1.32 • n=107 Participants
18.84 years
STANDARD_DEVIATION 1.11 • n=206 Participants
18.7 years
STANDARD_DEVIATION 1.3 • n=7 Participants
Sex: Female, Male
Female
43 Participants
n=99 Participants
37 Participants
n=107 Participants
47 Participants
n=206 Participants
127 Participants
n=7 Participants
Sex: Female, Male
Male
50 Participants
n=99 Participants
49 Participants
n=107 Participants
44 Participants
n=206 Participants
143 Participants
n=7 Participants
Region of Enrollment
United States
93 participants
n=99 Participants
86 participants
n=107 Participants
91 participants
n=206 Participants
270 participants
n=7 Participants

PRIMARY outcome

Timeframe: Three months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Percentage of substance use days in prior three months.

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=66 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=70 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=66 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
Substance Use
45.67 percent days of drug use
Standard Deviation 43.24
53.60 percent days of drug use
Standard Deviation 40.76
49.38 percent days of drug use
Standard Deviation 40.66

PRIMARY outcome

Timeframe: Six months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Percentage of substance use days in prior three months

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=70 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=68 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=66 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
Substance Use
39.10 percent days of drug use
Standard Deviation 38.83
48.88 percent days of drug use
Standard Deviation 41.43
42.64 percent days of drug use
Standard Deviation 40.74

PRIMARY outcome

Timeframe: Twelve months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included int he analysis.

Percentage of substance use days in prior six months

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=69 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=64 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=71 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
Substance Use
49.25 percent days of drug use
Standard Deviation 41.55
44.33 percent days of drug use
Standard Deviation 39.31
38.46 percent days of drug use
Standard Deviation 39.84

SECONDARY outcome

Timeframe: Three months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Frequency of condoms use in prior three months.

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=58 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=66 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=57 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
HIV Risk
19 participants who always used condom
26 participants who always used condom
25 participants who always used condom

SECONDARY outcome

Timeframe: Six months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Frequency of condoms use in prior three months.

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=58 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=62 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=65 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
HIV Risk
25 participants who always used condoms
29 participants who always used condoms
25 participants who always used condoms

SECONDARY outcome

Timeframe: Twelve months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Frequency of condoms use in prior six months.

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=53 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=59 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=63 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
HIV Risk
17 participants who always used condoms
18 participants who always used condoms
24 participants who always used condoms

SECONDARY outcome

Timeframe: Three months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Beck Depression Inventory - II (BDI-II) total score, range from 0 (no depresion)to 63 (severe depression)

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=66 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=70 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=66 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
Depressive Symptoms
9.63 units on a scale
Standard Deviation 9.57
14.78 units on a scale
Standard Deviation 14.83
10.97 units on a scale
Standard Deviation 12.20

SECONDARY outcome

Timeframe: Six months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Beck Depression Inventory - II (BDI - II) Range from 0 (no depression) to 63 (severe depression)

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=66 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=70 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=68 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
Depressive Symptoms
10.02 units on a scale
Standard Deviation 9.94
11.97 units on a scale
Standard Deviation 14.13
8.76 units on a scale
Standard Deviation 10.09

SECONDARY outcome

Timeframe: Twelve months

Population: The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. All available data were included in the analysis.

Beck Depression Inventory - II (BDI-II) total score, range from 0 (no depression)to 63 (severe depression)

Outcome measures

Outcome measures
Measure
MET + HIV Prevention
n=64 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
CRA + HIV Prevention
n=71 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews. the groups equally.
Case Management + HIV Prevention
n=69 Participants
The number of participants does not correspond to the participant flow model because some participants did not complete all follow-up assessment interviews.
Depressive Symptoms
8.70 units on a scale
Standard Deviation 11.09
12.07 units on a scale
Standard Deviation 12.13
8.48 units on a scale
Standard Deviation 10.93

Adverse Events

CRA + HIV Prevention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

MET + HIV Prevention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Case Management + HIV Prevention

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Natasha Slesnick

The Ohio State University

Phone: 614 247-8469

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place