Correlation Between Release of Cytokines From Liver Graft and Hemodynamic Instability

NCT01120743 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 17

Last updated 2017-11-24

No results posted yet for this study

Summary

The primary goal of this project is to identify the source of cytokines that are released into circulation during graft reperfusion. Seventeen patients scheduled to have adult cadaveric liver transplantation at the Milton S. Hershey Medical Center were contacted as prospective participants. Blood samples were obtained from the radial artery, the portal vein, and from the graft irrigation. The level of pro-inflammatory cytokines was verified and compared with the amount of catecholamines used to maintain hemodynamic stability.

Conditions

  • Liver Transplantation

Sponsors & Collaborators

  • Penn State University

    lead OTHER

Principal Investigators

  • Dmitri Bezinover, MD, PhD · Penn State Milton S. Hershey Medical Center, Penn State College of Medicine

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-08-31
Primary Completion
2010-04-30
Completion
2010-04-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01120743 on ClinicalTrials.gov