MedTrace Logo

Impact of Cranioplasty On Cerebral Perfusion

NCT01113645 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2013-05-01

No results posted yet for this study

Summary

The purpose of this study is to examine the impact of cranioplasty on cerebral hemodynamic and blood flow as prognostic factor in patients receiving decompressive craniectomy for Head injuries, Subarachnoid haemorrhage, intra-cerebral haemorrhage, cerebral dural sinus thrombosis, malignant middle cerebral artery stroke.

Conditions

  • Head Injuries
  • Subarachnoid Haemorrhage
  • Intra-cerebral Haemorrhage
  • Cerebral Thrombosis
  • Infarction, Middle Cerebral Artery

Interventions

PROCEDURE

Cerebral perfusion evaluation

The patient who received a craniectomy is included in the study and an information notice given to him. All patients are evaluated by GOS (Glasgow Outcome Score) and neurocognitive tests by FAB (frontal assessment battery) and MMSE (mini mental state examination) scores 1 week prior and 6 and 24 weeks post cranioplasty. Furthermore, hemodynamic monitoring is performed by CT perfusion scan (with quantitative assessment of global and local cerebral flow) 1 week prior and 6 weeks post cranioplasty, as well as by trans-cranial Doppler 1 week prior and 6 and 24 weeks post cranioplasty.

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Salvatore CHIBBARO, MD · Assistance Publique - Hôpitaux de Paris

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-07-31
Primary Completion
2011-12-31
Completion
2012-04-30

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01113645 on ClinicalTrials.gov