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Characterization of Proliferating Compartment in B-Cell Patients and in Healthy Aging Subjects

NCT01110863 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2021-03-03

No results posted yet for this study

Summary

By ingesting a non-radioactive and non-toxic compound "heavy water" for 6 weeks, the DNA of newly developed cells in the body of subjects with B-cell chronic lymphocytic leukemia can be labeled and followed by performing routine blood draws at specified time intervals. By using mass spectrometric analysis we can measure how quickly new B-CLL cells are generated in the bone marrow and how quickly they leave the blood, a measure of cell turnover. This will help us to better understand the unique characteristics of this disease process.

Conditions

Sponsors & Collaborators

  • Northwell Health

    lead OTHER

Principal Investigators

  • Nicholas Chiorazzi, MD · Feinstein Institute for Medical Research

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-12-31
Primary Completion
2016-02-12
Completion
2016-02-12

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01110863 on ClinicalTrials.gov