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Cerebrovascular Reactivity in Hepatic Encephalopathy

NCT01099293 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2012-05-21

No results posted yet for this study

Summary

It has been observed that patients with cirrhosis present a generalized state of vasoconstriction as an homeostatic response to splanchnic arteriolar vasodilatation. On progression of the disease, vascular regulation is mismatched, causing altered systemic blood flow and lose in the cerebrovascular reactivity.

The investigators hypothesize that the altered cerebrovascular reactivity induces neurological disturbances related to hepatic encephalopathy and, therefore, the existence of a correlation between cerebrovascular reactivity and the stage of hepatic encephalopathy.

Conditions

  • Hepatic Encephalopathy

Sponsors & Collaborators

  • National Council of Science and Technology, Mexico

    collaborator OTHER

  • Secretaria de Salud, Mexico

    collaborator OTHER_GOV

  • Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

    lead OTHER

Principal Investigators

  • Aldo Torre-Delgadillo, M.D., M.Sc. · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Eligibility

Min Age
18 Years
Max Age
69 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-03-31
Primary Completion
2011-06-30
Completion
2011-09-30

Countries

  • Mexico

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01099293 on ClinicalTrials.gov