The Chloroquine for Influenza Prevention Trial
NCT01078779 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 1516
Last updated 2010-03-02
Summary
A randomised controlled trial to determine the efficacy of chloroquine for the prevention of influenza
Conditions
Interventions
- DRUG
-
Chloroquine
Chloroquine phosphate 250mg capsule, two capsules daily for 7 days then 2 capsules once a week for a total treatment duration of 12 weeks
- DRUG
-
Placebo capsules, 2 capsules daily for 7 days then 2 capsules weekly for a total treatment duration of 12 weeks
Sponsors & Collaborators
-
National University Hospital, Singapore
lead OTHER
Principal Investigators
-
Nicholas I Paton, MD FRCP · National University of Singapore
-
Lawrence Lee, MD PhD · National University of Singapore
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-11-30
- Primary Completion
- 2010-05-31
- Completion
- 2010-08-31
Countries
- Singapore
Study Locations
More Related Trials
-
Study to Assess the Safety and Efficacy of ZX-7101A in Adolescents With Influenza
NCT06099873 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19
NCT04420247 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Hydroxycholoroquine Compared to Placebo as Treatment for People With COVID-19
NCT04379492 ·Status: WITHDRAWN ·Phase: PHASE2
-
Hydroxychloroquine Use in Hospitalized Patients With COVID-19: Impact on Progression to Severe or Critical Disease
NCT04429867 ·Status: UNKNOWN ·Phase: PHASE4
-
Phase1 Study of GR121167, Single and Multiple Dose Study in Healthy Japanese Males
NCT01428479 ·Status: COMPLETED ·Phase: PHASE1
-
Assessing Hydroxychloroquine in Patients With SARS-CoV-2 (COVID-19)
NCT04363866 ·Status: WITHDRAWN ·Phase: PHASE2
-
A Randomised Controlled Trial on the Effect of Post-exposure Oseltamivir Prophylaxis on Influenza Transmission in Nursing Homes
NCT01053377 ·Status: UNKNOWN ·Phase: PHASE4
-
Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis
NCT04597775 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Efficacy and Tolerability of Hydroxychloroquine in Adult Patients With COVID-19
NCT04384380 ·Status: COMPLETED ·Phase: NA
-
A Phase II, Multicenter, Randomized, Placebo -Controlled, Study To Evaluate The Efficacy and Safety Of Intramuscular Peramivir 600 mg In Subjects With Uncomplicated Acute Influenza
NCT00705406 ·Status: COMPLETED ·Phase: PHASE2
-
To Assess the Efficacy of GP681 Tablet Versus Placebo in Patients With Acute Uncomplicated Influenza Virus Infection
NCT05474755 ·Status: COMPLETED ·Phase: PHASE3
-
Hydroxychloroquine Chemoprophylaxis for COVID-19 Infection in High-risk Healthcare Workers.
NCT04370015 ·Status: UNKNOWN ·Phase: NA
-
Efficacy and Safety of ZSP1273 in Children 12-17 Years Old With Influenza A
NCT07229820 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP)
NCT04328961 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19
NCT04447534 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment of COVID-19 Cases and Chemoprophylaxis of Contacts as Prevention
NCT04304053 ·Status: COMPLETED ·Phase: PHASE3
-
Hydroxychloroquine Versus Placebo in COVID-19 Patients at Risk for Severe Disease
NCT04325893 ·Status: TERMINATED ·Phase: PHASE3
-
Study to Assess the Efficacy and Safety of GP681 Versus Placebo for Postexposure Prophylaxis Against Influenza
NCT06574503 ·Status: RECRUITING ·Phase: PHASE3
-
The Safety, Tolerability and Pharmacokinetic Study of ZSP1273 in Healthy Volunteers.
NCT03679143 ·Status: COMPLETED ·Phase: PHASE1
-
High-dose Hydroxychloroquine for the Treatment of Ambulatory Patients With Mild COVID-19
NCT04351620 ·Status: COMPLETED ·Phase: PHASE1
-
Hydroxychloroquine for Treatment of Non-Severe COVID-19
NCT04860284 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of ZX-7101A Tablets in Adults with Uncomplicated Influenza
NCT05702489 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Safety and Efficacy of Oseltamivir in Children Younger Than One Year of Age
NCT01037634 ·Status: WITHDRAWN ·Phase: PHASE2
-
Hydroxychloroquine to Prevent SARS-CoV-2 Infection/COVID-19
NCT04414241 ·Status: COMPLETED ·Phase: PHASE3
-
Double-blind Study to Evaluate the Safety and Efficacy of Antroquinonol in Mild-Moderate COVID-19 Hospitalized Patients
NCT04523181 ·Status: COMPLETED ·Phase: PHASE2