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Host Genetic Susceptibility to Avian Influenza A/H5N1

NCT01074736 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2010-11-04

No results posted yet for this study

Summary

The identification and characterization of susceptibility loci for H5N1 infection in humans could have profound implications. The detection of host genetic factors may shed light on key pathogenic interactions between H5N1 and human cells, assisting in identifying the viral characteristics determining pandemic potential. In addition, the identification and verification of susceptibility loci would be followed by functional studies which might point the way to new therapeutic and preventive options.

The objective of this study is to investigate if host genetic factors are associated with susceptibility to influenza H5N1 illness

Conditions

  • Influenza A Virus/H5N1 Subtype

Sponsors & Collaborators

  • University of Oxford

    collaborator OTHER

  • Wellcome Trust

    collaborator OTHER

  • South East Asia Infectious Disease Clinical Research Network

    lead NETWORK

Principal Investigators

  • Tawee Chotpitayasunond, Professor · Queen Sirikit National Institute of Child Health, Bangkok, Thailand

  • Herawati Sudoyo, Dr. · Eijkman Institute for Molecular Biology

  • Tran Hien Nguyen, Professor · National Institute of Hygiene and Epidemiology, Hanoi, Vietnam

  • Martin Hibberd, Dr. · Genome Institute of Singapore, Singapore

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-07-31
Primary Completion
2010-08-31
Completion
2010-10-31

Countries

  • Vietnam

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01074736 on ClinicalTrials.gov