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Risk Factors and Biomarkers Associated With Recurrence After Excision of Primary Pterygium

NCT01068496 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 1

Last updated 2015-05-20

No results posted yet for this study

Summary

This study looks at global gene expression in pterygium and found the derangement of matrix genes in particular to be a feature of pterygium. In the investigators opinion, it would be more beneficial to elicit changes in gene expression before the recurrence of pterygium and by developing a panel of biomarkers that are associated with pterygium recurrence; one would be able to predict the post surgical prognosis of patients after resection.Biomarker levels will be compared to discover a biomarker panel for prediction of recurrence.

Conditions

  • Pterygium

Sponsors & Collaborators

  • Singapore Eye Research Institute

    collaborator OTHER

  • Singapore National Eye Centre

    lead OTHER_GOV

Principal Investigators

  • Samanthila Waduthantri · Singapore National Eye Centre

  • Laurence Lim, MBBS · Singapore National Eye Centre

  • Federico Luengo Gimeno · Singapore National Eye Centre

  • Jodhbir Mehta · Singapore National Eye Centre

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-03-31
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01068496 on ClinicalTrials.gov