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Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen

NCT01061853 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 76

Last updated 2013-10-16

No results posted yet for this study

Summary

The purpose of this study is to determine wether topical rapamycin is more efficient than topical steroids in the treatment of chronic erosive lichen planus.

Conditions

  • Oral Lichen Planus

Interventions

DRUG

TOPICAL SIROLIMUS (RAPAMUNE*)

APPLICATION ON THE LESIONS OF TOPICAL SIROLIMUS (RAPAMUNE\*)1mg/ml bid during 3 months

DRUG

TOPICAL BETAMETHASONE 0.05%

APPLICATION ON THE LESIONS OF TOPICAL BETAMETHASONE (DIPROLENE\*)0.05% bid during 3 months

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    collaborator OTHER_GOV

  • University Hospital, Tours

    lead OTHER

Principal Investigators

  • Loïc VAILLANT, MD · Centre 1-TOURS

  • Camille FRANCES, MD · Centre-2 Tenon

  • Scarlette AGBO-GODEAU, MD · Centre-3 La Pitié-Salpêtrière

  • Liliane LAROCHE, MD · Centre-4 Avicenne

  • Francis PASCAL, MD · Centre-5 St-Louis

  • Emmanuel DELAPORTE, MD · Centre-6 Lille

  • Alain TAÏEB, MD · Centre-7 Bordeaux

  • Jean-Philippe DELACOUR, MD · Centre -8 Nice

  • Philippe BERNARD, MD-PHD · Centre-9 REIMS

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-02-29
Primary Completion
2012-11-30
Completion
2012-11-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01061853 on ClinicalTrials.gov