Tolerability Comparison of Differin® Cream 0.1% Versus Differin® Lotion 0.1% in Subjects With Healthy Skin
NCT01046396 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 69
Last updated 2022-08-01
Summary
The purpose of this study is to compare the tolerability of Differin® (adapalene) Cream, 0.1% to Differin® Lotion, 0.1% in subjects with healthy skin treated once a day for three (3) weeks.
Conditions
- Skin Manifestations
Interventions
- DRUG
-
adapalene cream 0.1% and adapalene lotion 0.1%
adapalene cream 0.1% - apply once daily on one side of the face for 3 weeks
- DRUG
-
adapalene lotion 0.1%
adapalene lotion 0.1% - apply once daily on the opposite side of the face for 3 weeks
Sponsors & Collaborators
-
Galderma R&D
lead INDUSTRY
Principal Investigators
-
Ronald W Gottschalk, MD · Galderma R&D
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-01-31
- Primary Completion
- 2010-02-28
- Completion
- 2010-02-28
Countries
- United States
Study Locations
More Related Trials
-
A Study Comparing Adapalene Gel 0.1% and to Differin Gel in the Treatment of Acne Vulgaris
NCT04797793 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Differin® Gel x12 Wks vs Tazorac® Cream x12 Wks vs Differin® x6 Wks Switched to Tazorac® x6 Wks for Treatment of Acne
NCT00469755 ·Status: COMPLETED ·Phase: PHASE4
-
Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage
NCT00647556 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Endpoint Bioequivalence Study of Adapalene Gel 0.1%
NCT04329403 ·Status: WITHDRAWN ·Phase: PHASE3
-
Study Comparing Adapalene Gel 0.3% to Differin® and Both to a Placebo Control in Treatment of Acne Vulgaris
NCT02411942 ·Status: COMPLETED ·Phase: PHASE1
-
Split-face Tolerability Comparison Between Adapalene-Benzoyl Peroxide Gel Versus Tretinoin Gel
NCT01522456 ·Status: COMPLETED ·Phase: PHASE4
-
Bioequivalence of Adapalene Topical Gel in Patients With Acne Vulgaris
NCT01182636 ·Status: COMPLETED ·Phase: PHASE1
-
Management of Side-Effects of Anti-Acne Treatment by a Cosmetic Routine
NCT05486910 ·Status: COMPLETED
-
Adjunctive Usage of a Moisturizing Lotion (Cetaphil® Moisturizing Lotion) to Limit the Skin Irritation Linked to the Set-Up of a Treatment by Topical Retinoid (Differin® Gel 0,1%) in Healthy Subjects of Chinese Origins
NCT00971282 ·Status: COMPLETED ·Phase: PHASE4
-
Analysis of Adherence in Subjects Undergoing Differin Gel, 0.1% Treatment of Moderate to Severe Acne Vulgaris
NCT00696449 ·Status: COMPLETED ·Phase: PHASE4
-
Bioequivalence Study of Adapalene Gel 0.3% in Subjects With Facial Acne Vulgaris
NCT03650361 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy, Safety Profile, and Post-Acne Sequelae of 0.025% Retinoic Acid Cream vs. 0.1% Adapalene Cream in Mild Acne Vulgaris in Fitzpatrick Skin Types III-V
NCT07015931 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Analysis of Adherence & Associated Factors in Teenagers Undergoing Treatment of Acne Vulgaris With Differin® Gel 0.1%
NCT00437151 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacokinetics Study of Dapsone-Adapalene Fixed Combination Gel in Acne
NCT01425320 ·Status: WITHDRAWN ·Phase: PHASE1
-
Study for Long-term Treatment of Acne Vulgaris With Skinoren Versus Differin
NCT01387048 ·Status: COMPLETED ·Phase: PHASE4
-
A Bioavailability Study of DFD-03 Compared to Tazorac® in Patients With Moderate Acne Vulgaris
NCT03599193 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Fixed Combination Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel in the Treatment of Acne Vulgaris
NCT00441415 ·Status: COMPLETED ·Phase: PHASE3
-
Combination Therapy With Differin® Gel 0.3% and Duac® (Clindamycin/Benzoyl Peroxide Gel) in Subjects With Acne Vulgaris
NCT00671749 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and the Tolerability of the Sequential Application of Two Marketed Products in Patients With Acne Vulgaris
NCT01461655 ·Status: COMPLETED ·Phase: PHASE2
-
Assessment of Subjects' Efficacy and Experiences Using Adapalene BPO Gel in the Treatment of Acne Vulgaris
NCT01209949 ·Status: COMPLETED ·Phase: PHASE4
-
Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications
NCT00926367 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of Irritation by Two Facial Gels Applied to Opposite Sides of the Face
NCT00919191 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Epiduo Associated With Lymecycline Versus Epiduo Vehicle Associated With Lymecycline in Acne Vulgaris
NCT01014689 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Safety and Local Tolerability of DFD-03 (Tazarotene) Lotion, 0.1% Compared to Tazorac® Cream, 0.1% in the Topical Treatment of Acne Vulgaris
NCT03341910 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of CD5789 (Trifarotene) 50μg/g Cream Versus Vehicle Cream in Acne Vulgaris
NCT02566369 ·Status: COMPLETED ·Phase: PHASE3